abstract：BACKGROUND:The NOL index is based on multiparametric analysis of heart rate (HR), skin conductance, wave plethysmography, and their time derivative. The aim of this study was to evaluate the NOL to detect standardized nociceptive stimuli with various remifentanil dosages under general anesthesia. METHODS:A prospective...

journal_title：Minerva anestesiologica

authors： Stöckle PA,Julien M,Issa R,Décary E,Brulotte V,Drolet P,Henri M,Poirier M,Latulippe JF,Dorais M,Verdonck O,Fortier LP,Richebé P

更新日期：2018-10-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) commonly affects intensive care unit patients and is associated with high mortality. In addition to etiologic treatment and protective ventilation, non-ventilatory therapies represent a significant part of ARDS care. Pharmacological treatments, extra corporeal devices and pro...

journal_title：Minerva anestesiologica

authors： Bourenne J,Hraiech S,Rambaud R,Forel JM,Persico N,Guervilly C,Papazian L

更新日期：2018-09-01 00:00:00

abstract：:Cannabinoids appear to possess many potential medical uses, which may extend to pain control. A narrative review of the literature has found a variety of studies testing botanical and synthetic cannabinoids in different pain syndromes (acute pain, cancer pain, chronic noncancer pain, fibromyalgia pain, migraine, neuro...

journal_title：Minerva anestesiologica

authors： Pergolizzi JV Jr,Lequang JA,Taylor R Jr,Raffa RB,Colucci D,NEMA Research Group.

更新日期：2018-08-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a global public health epidemic. It represents the principal cause of death and disability in individuals aged under 35 in the USA. In the subacute phase, severe TBI patients who recover consciousness go through a state of agitation and delirium. However, there is only limited research ...

journal_title：Minerva anestesiologica

authors： Ganau M,Lavinio A,Prisco L

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:The world population is mostly male at birth, although there is a shift in predominance over 55 years of age with more females than males. Male gender was recently hypothesized to be a risk factor for sepsis and septic shock; the reasons and the consequences of this odd discrepancy are yet a matter of deba...

journal_title：Minerva anestesiologica

authors： Campanelli F,Landoni G,Cabrini L,Zangrillo A

更新日期：2018-04-01 00:00:00

abstract：:Over the last two decades, lung transplantation emerged as the standard of care for patients with advanced and terminal lung disease. Despite the increment in lung transplantation rates, in 2016 the overall mortality while on waiting list in Italy reached 10%, whereas only 39% of the wait-list patients were successful...

journal_title：Minerva anestesiologica

authors： Sales G,Costamagna A,Fanelli V,Boffini M,Pugliese F,Mascia L,Brazzi L

更新日期：2018-02-01 00:00:00

abstract：:This review focuses on recent developments in preservation techniques in liver transplantation. First, we discuss mechanisms of organ injury when using high-risk organs, including donation after circulatory death and steatotic grafts and we summarize pathways of ischemia reperfusion injury together with their link to ...

journal_title：Minerva anestesiologica

authors： Schlegel AA,Kalisvaart M,Muiesan P

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:The study aimed to compare Bispectral Index (BIS) and non-BIS anesthetic protocols on postoperative recovery outcomes. EVIDENCE ACQUISITION:Medline, PubMed, Cochrane, EMBASE, and Google Scholar databases were searched until January 21, 2016. EVIDENCE SYNTHESIS:Twenty-six studies were included with a tota...

journal_title：Minerva anestesiologica

authors： Chiang MH,Wu SC,Hsu SW,Chin JC

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:There is an equipoise regarding closed-loop ventilation modes and the ability to reduce workload for providers. On one hand some settings are managed by the ventilator but on another hand the automatic mode introduces new settings for the user. METHODS:This randomized controlled trial compared the number of...

journal_title：Minerva anestesiologica

authors： Arnal JM,Garnero A,Novotni D,Corno G,Donati SY,Demory D,Quintana G,Ducros L,Laubscher T,Durand-Gasselin J

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the CNS and well-known target for general anesthetics. In addition, the dysregulation of GABA could be involved in the etiology of major depressive disorder (MDD). In this study, we aimed to determine whether MDD has any effect on anest...

journal_title：Minerva anestesiologica

authors： Erden V,Güler C,Seven S,Bağ S,Kara AG,Kirgezen Ş

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Ultrasound is a portable and safe technology that is increasingly used to assist anesthetic procedures and has been integrated into the routine practice of a wide range of invasive procedures. As a complementary diagnostic tool, publications related to perioperative support other than vascular access and n...

journal_title：Minerva anestesiologica

authors： Ferreira Albuquerque Costa NT,Gomar Sancho C

更新日期：2018-01-01 00:00:00

abstract：:Stroke is a devastating complication that is difficult to diagnose in the perioperative setting because of the effects of anesthetic and analgesic agents. Lingering anesthesia effects hinder clinicians in identifying stroke symptoms, frequently resulting in a delay in diagnosis and treatment and in unfavorable outcome...

journal_title：Minerva anestesiologica

authors： Pai SL,Wang RD,Aniskevich S

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:General anesthesia utilizing inhalational agents without intravenous (IV) access for minor procedures is controversial. Eliminating IV access increases efficiency and patient satisfaction; however, the ability to introduce rapid acting medications into the circulation during an unanticipated emergency become...

journal_title：Minerva anestesiologica

authors： Hung CW,Licina L,Abramson DH,Arslan-Carlon V

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate long-term outcomes, posthospital trajectories, and quality of life (QOL) in patients ≥80 years admitted to the Intensive Care Unit (ICU) of a tertiary care hospital. METHODS:A 1-year prospective observational cohort analysis was performed. All consecutive patients ≥8...

journal_title：Minerva anestesiologica

authors： Oeyen S,Vermassen J,Piers R,Benoit D,Annemans L,Decruyenaere J

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Multiple organ dysfunction can occur in patients undergoing Veno-arterial Extra Corporal Membrane Oxygenation (VA-ECMO); however, liver function has not been well studied in this setting. METHODS:In a review of our institutional ECMO database (n=162), we collected aspartate (AST) and alanine (ALT) transamin...

journal_title：Minerva anestesiologica

authors： Blandino Ortiz A,Lamanna I,Antonucci E,Pozzebon S,Dell'anna AM,Vincent JL,DE Backer D,Taccone FS

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The majority of authors and the literature recommend sugammadex dose to be calculated according to RBW without taking fat content into consideration. Our aim was to compare the efficacy and safety of sugammadex at doses of 1.5, 2, and 4 mg/kg, calculated according to ideal body weight basis, for the reversal...

journal_title：Minerva anestesiologica

authors： Abd El-Rahman AM,Othman AH,El Sherif FA,Mostafa MF,Taha O

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Goal-directed fluid management using stroke volume variation (SVV) analysis is not well studied in free flap reconstruction surgery in patients with head and neck cancer. METHODS:Patients operated due to cancer of the head and neck with free flap reconstruction during 2008-2010 and 2012-2014 in Oulu Univers...

journal_title：Minerva anestesiologica

authors： Lahtinen SL,Liisanantti JH,Poukkanen MM,Laurila PA

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:We hypothesized that the use of the channeled King Vision™ and Airtraq® would shorten the time for tracheal intubation compared with the Macintosh or GlideScope® laryngoscopes in patients with normal airways. METHODS:Eighty-six patients were randomly assigned to intubate the trachea using either the Macinto...

journal_title：Minerva anestesiologica

authors： Al-Ghamdi AA,El Tahan MR,Khidr AM

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Recent data found that perioperative goal directed therapy (GDT) was effective only in higher control mortality rates (>20%) with a relatively high heterogeneity that limited the strength of evidence. The aim of the present meta-analysis was to clearly understand which high risk patients may benefit of GDT...

journal_title：Minerva anestesiologica

authors： Giglio M,Manca F,Dalfino L,Brienza N

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Today, most of the pre-emptive hemodynamic optimization algorithms are based on variables associated with invasive techniques like arterial cannulation. The non-invasive Nexfin™ technology is able to estimate continuous Cardiac Index (CI) and pulse pressure variation (PPV). However, the efficiency of an earl...

journal_title：Minerva anestesiologica

authors： Broch O,Carstens A,Gruenewald M,Nischelsky E,Vellmer L,Bein B,Aselmann H,Steinfath M,Renner J

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Local anesthetics (LA) work by blocking sodium conductance through voltage-gated sodium channels. Complete local anesthetic resistance is infrequent, and the cause is unknown. Genetic variation in sodium channels is a potential mechanism for local anesthetic resistance. A patient with a history of inadequate...

journal_title：Minerva anestesiologica

authors： Clendenen N,Cannon AD,Porter S,Robards CB,Parker AS,Clendenen SR

更新日期：2016-10-01 00:00:00

abstract：:A randomized, multicenter trial conducted in 32 northern European general intensive care units (ICUs) enrolled some patients with septic shock randomly assigned to receive a red blood cell transfusion when the hemoglobin (Hb) level was ≤7 g/dL ("lower threshold"; N.=502) or ≤9 g/dL ("higher threshold"; N.=496) through...

journal_title：Minerva anestesiologica

authors： Lelubre C,Vincent JL,Taccone FS

更新日期：2016-09-01 00:00:00

abstract：INTRODUCTION:Application of mechanical ventilation in spontaneously breathing children remains a challenge for several reasons: mainly, small tidal volumes and high respiratory rates, especially in the presence of leaks, interfere with patient-ventilator synchrony. Leaks also cause unreliable monitoring of respiratory ...

journal_title：Minerva anestesiologica

authors： Beck J,Emeriaud G,Liu Y,Sinderby C

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The aim was to ascertain the prognostic value of mid-regional pro-adrenomedullin (MR-proADM), measured within 24 hours from the onset of septic shock (SS). METHODS:We performed a prospective, observational study on all patients admitted to our hospital's Intensive Care Unit with SS over a one year period fr...

journal_title：Minerva anestesiologica

authors： DE LA Torre-Prados MV,Garcia-DE LA Torre A,Enguix A,Mayor-Reyes M,Nieto-González M,Garcia-Alcantara A

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Evidences supporting the use of ICP monitoring after aneurysmal subarachnoid hemorrhage (aSAH) are limited. The aim of our paper is to examine whether elevated intracranial pressure (ICP) and ICP-derived variables predict mortality and functional outcomes after aSAH. METHODS:A systematic review of the liter...

journal_title：Minerva anestesiologica

authors： Cossu G,Messerer M,Stocchetti N,Levivier M,Daniel RT,Oddo M

更新日期：2016-04-05 00:00:00

abstract：:Two large phase-III prospective, multicenter, controlled, double-blind, randomized clinical trials (the PROTECT III study; the SYNAPSE study) evaluated the effectiveness of an early administration of progesterone in patients with moderate to severe traumatic brain injury (TBI). In the PROTECT III Trial, patients were ...

journal_title：Minerva anestesiologica

authors： Meyfroidt G,Taccone FS

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Physical and mental workload during cardiopulmonary resuscitation (CPR) is challenging under extreme working conditions. We hypothesized that the mechanical chest-compression device Lund University Cardiac Assist System (LUCAS) increases the effectiveness of CPR, decreases the physical workload and improves ...

journal_title：Minerva anestesiologica

authors： Rehatschek G,Muench M,Schenk I,Dittrich W,Schewe JC,Dirk C,Hering R

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Overall medical complications have been reduced after fast-track total hip (THA) and knee arthroplasty (TKA), but data on specific renal and urological (RU) complications are limited. METHODS:To describe the incidence and consequences of serious RU complications resulting in length of stay > 4 days or 30-da...

journal_title：Minerva anestesiologica

authors： Bjerregaard LS,Jorgensen CC,Kehlet H,Lundbeck Foundation Centre for Fast-Track Hip and Knee Replacement Collaborative Group.

更新日期：2016-03-30 00:00:00

abstract：:Pulmonary complications are a source of greater postoperative morbidity and mortality and longer hospital stays. Although many factors have been implicated as predictors, few models have been developed with the rigorous methodology required for clinically useful tools. In this article we attempt to describe what to lo...

journal_title：Minerva anestesiologica

authors： Mazo V,Sabaté S,Canet J

更新日期：2016-03-01 00:00:00

abstract：:Early strategies to diagnose, manage and predict outcome of sepsis are essential to further improve morbidity and mortality of sepsis. Whereas biomarkers have become mainstay in other fields of medicine, their clinical utility in sepsis remains generally much less proven and so biomarkers are much less used clinically...

journal_title：Minerva anestesiologica

authors： Douglas JJ,Roussel JA

更新日期：2016-03-01 00:00:00

abstract：:Modulation of inflammatory and immune response to critical illness has been the goal of much research in the last decade and a variety of drugs and nutrients (so called "immunonutrients") have been tested in experimental models with promising results. Though, in the clinical setting of intensive care, their efficacy h...

journal_title：Minerva anestesiologica

authors： Annetta MG,Pittiruti M,Vecchiarelli P,Silvestri D,Caricato A,Antonelli M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Numerous animal models have demonstrated neuronal damage resulting from anesthetic exposure in the developing brain. Studies have shown a relationship between anesthetic exposure and brain hypoxia, neurodegeneration and apoptosis. The relevance of data derived from controlled experimental studies to human ne...

journal_title：Minerva anestesiologica

authors： Green MS,Aman MM,Stevens L,Voralu K,Saththasivam P,Mychaskiw G,Katsetos CD

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Labile iron is important in the pathogenesis of acute kidney injury (AKI). Neutrophil gelatinase-associated lipocalin (NGAL) and hepcidin control iron metabolism and are upregulated during renal stress. However, higher levels of urinary NGAL are associated with AKI severity whereas higher urinary hepcidin le...

journal_title：Minerva anestesiologica

authors： Mårtensson J,Glassford NJ,Jones S,Eastwood GM,Young H,Peck L,Ostland V,Westerman M,Venge P,Bellomo R

更新日期：2015-11-01 00:00:00

abstract：:The overall use of allogeneic blood transfusions in clinical practice remains relatively high and still varies widely among centres and practitioners. Moreover, allogeneic blood transfusions have historically been linked with risks and complications: some of them (e.g. transfusion reactions and transmission of pathoge...

journal_title：Minerva anestesiologica

authors： Liumbruno GM,Vaglio S,Grazzini G,Spahn DR,Biancofiore G

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:When patients are incompetent, advance directives (AD) can help physicians take crucial medical decisions. However, prevalence remains low. The objective was to investigate physicians' perspectives and attitudes towards AD in order to determine potential targets for improvement. METHODS:Observational study ...

journal_title：Minerva anestesiologica

authors： Gigon F,Merlani P,Ricou B

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The flexible fiberoptic bronchoscope (FOB) is viewed as the gold standard device for awake intubation in the difficult airway. The newer rigid flexible laryngoscope (RIFL) was developed for similar indications. In this study we compare these two devices for management of potentially difficult airways after i...

journal_title：Minerva anestesiologica

authors： Alvis BD,King AB,Hester D,Hughes CG,Higgins MS

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Studies on pregnant women undergoing cesarean delivery or elderly men scheduled for prostate brachytherapy have demonstrated the predictive value of heart rate variability (HRV) analysis for hypotension during spinal anesthesia. We conducted a prospective observational study to investigate if preoperative HR...

journal_title：Minerva anestesiologica

authors： Raimondi F,Colombo R,Spazzolini A,Corona A,Castelli A,Rech R,Borghi B,Fossali T,Guzzetti S

更新日期：2015-07-01 00:00:00

abstract：:Cardiac surgery patients often develop a restrictive pulmonary impairment and gas exchange abnormalities in the early postoperative period. Chest physiotherapy is routinely prescribed in order to reduce or prevent these complications. Besides early mobilization, positioning and shoulder girdle exercises, various breat...

journal_title：Minerva anestesiologica

authors： Westerdahl E

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Clinical studies have raised concerns about the safety of 6% hydroxyethylstarch (HES) 130/0.42, but the pathomechanisms of this renal impairment remain unknown. To evaluate the effects of different HES concentrations, molar substitutions and molecular weights in HES-induced renal impairment, we used a porcin...

journal_title：Minerva anestesiologica

authors： Simon TP,Thiele C,Schuerholz T,Fries M,Stadermann F,Haase G,Amann KU,Marx G

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:We prospectively evaluated the effect of insertion angle on the visibility of echogenic and nonechogenic needles in phantoms and in axillary nerve blocks in patients. METHODS:Conventional and echogenic needles were studied in phantoms at insertion angles of 0-30°, 30-45°, and ≥ 45°. Operators rated comfort ...

journal_title：Minerva anestesiologica

authors： Abbal B,Choquet O,Gourari A,Bouic N,Massone A,Biboulet P,Bringuier S,Capdevila X

更新日期：2015-04-01 00:00:00